Day hotels available in Otay Mesa: 16Sort by:PopularityPorto Vista Hotel In Little ItalyPreviousNextPool access includedPorto Vista Hotel In Little ItalySee on mapLittle Italy4.2/5 | 40 ReviewsFree cancellationPayment at the hotelCA$124-51%CA$251 per nightFree cancellationPayment at the hotelFromCA$124-51%CA$251 per nightPrevious8am - 2pm10am - 5pm3pm - 11pmNextThe Guild Hotel, San Diego, A Tribute Portfolio Hotel by MarriottPreviousNextThe Guild Hotel, San Diego, A Tribute Portfolio Hotel by MarriottSee on mapCore-Columbia4.5/5 | 16 ReviewsFree cancellationPayment at the hotelCA$187-33%CA$279 per nightFree cancellationPayment at the hotelFromCA$187-33%CA$279 per nightPrevious8am - 2pm10am - 5pmNextDays Inn by Wyndham San Diego/Downtown/Convention CenterPreviousNextDays Inn by Wyndham San Diego/Downtown/Convention CenterSee on mapCore-Columbia4/5 | 32 ReviewsFree cancellationPayment at the hotelCA$111-58%CA$263 per nightFree cancellationPayment at the hotelFromCA$111-58%CA$263 per nightPrevious9am - 4pmNextMotel 6-San Diego, CA - DowntownPreviousNextMotel 6-San Diego, CA - DowntownSee on mapCoronado4.1/5 | 10 ReviewsFree cancellationPayment at the hotelCA$84-34%CA$125 per nightFree cancellationPayment at the hotelFromCA$84-34%CA$125 per nightPrevious8am - 2pm9am - 4pm1pm - 7pm5pm - 10pmNextManchester Grand Hyatt San DiegoPreviousNextPool access includedManchester Grand Hyatt San DiegoSee on mapMarina4.7/5 | 33 ReviewsFree cancellationPayment at the hotelCA$314-36%CA$488 per nightFree cancellationPayment at the hotelFromCA$314-36%CA$488 per nightPrevious9am - 5pm11am - 6pmNextResidence Inn by Marriott San Diego DowntownPreviousNextPool access includedResidence Inn by Marriott San Diego DowntownSee on mapLittle Italy4.6/5 | 14 ReviewsFree cancellationPayment at the hotelCA$209-35%CA$319 per nightFree cancellationPayment at the hotelFromCA$209-35%CA$319 per nightPrevious10am - 5pmNextHoliday Inn Express - Downtown San Diego, an IHG HotelPreviousNextPool access includedHoliday Inn Express - Downtown San Diego, an IHG HotelSee on mapCortez HillFree cancellationPayment at the hotelCA$173-39%CA$283 per nightFree cancellationPayment at the hotelFromCA$173-39%CA$283 per nightPrevious10am - 5pmNextBaymont by Wyndham San Diego DowntownPreviousNextBaymont by Wyndham San Diego DowntownSee on mapCore-Columbia4.4/5 | 12 ReviewsFree cancellationPayment at the hotelCA$105-56%CA$236 per nightFree cancellationPayment at the hotelFromCA$105-56%CA$236 per nightPrevious10am - 4pmNextThe Bristol Hotel San DiegoPreviousNextThe Bristol Hotel San DiegoSee on mapCore-Columbia4.7/5 | 7 ReviewsFree cancellationPayment at the hotelCA$145-26%CA$194 per nightFree cancellationPayment at the hotelFromCA$145-26%CA$194 per nightPrevious7am - 1pmNextCourtyard by Marriott San Diego DowntownPreviousNextCourtyard by Marriott San Diego DowntownSee on mapCore-Columbia4.8/5 | 13 ReviewsFree cancellationPayment at the hotelCA$249Free cancellationPayment at the hotelFromCA$249-17%CA$300 per nightPrevious7am - 6pm9am - 4pm10am - 6pmNextHampton Inn San Diego-DowntownPreviousNextPool access includedHampton Inn San Diego-DowntownSee on mapSan Diego, CA4.6/5 | 5 ReviewsFree cancellationPayment at the hotelCA$202-52%CA$417 per nightFree cancellationPayment at the hotelFromCA$202-52%CA$417 per nightPrevious10am - 4pmNextMargaritaville Hotel San Diego Gaslamp QuarterPreviousNextPool access includedMargaritaville Hotel San Diego Gaslamp QuarterSee on mapEast Village4.9/5 | 22 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromCA$138-67%CA$417 per nightSold out offersKimpton Hotel Palomar San DiegoPreviousNextPool access includedKimpton Hotel Palomar San DiegoSee on mapCore-Columbia4.8/5 | 7 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromCA$0Sold out offersThe El Cordova HotelPreviousNextPool access includedThe El Cordova HotelSee on mapCoronadoFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromCA$0Sold out offersRamada by Wyndham San Diego National CityPreviousNextPool access includedRamada by Wyndham San Diego National CitySee on mapNational City4.1/5 | 12 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromCA$0Sold out offersThe Westin San Diego BayviewPreviousNextPool access includedThe Westin San Diego BayviewSee on mapCore-Columbia4.7/5 | 29 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFromCA$0Sold out offers1